EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis

Metastatic and relapsed Ewing sarcoma typically afflicts the adolescent population and is largely fatal. These bone tumors are most commonly driven by the fusion oncoprotein EWS-FLI1. Ewing tumors demonstrate significant intra-tumoral heterogeneity, and individual tumor cells can express highly vari...

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Detalles Bibliográficos
Autores principales: Bailey, Kelly M., Julian, Claire M., Klinghoffer, Ariel N., Bernard, Heather, Lucas, Peter C., McAllister-Lucas, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534359/
https://www.ncbi.nlm.nih.gov/pubmed/31164960
http://dx.doi.org/10.18632/oncotarget.26939

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