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Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity
Enhancers are important regulatory elements that can control gene activity across vast genetic distances. However, the underlying nature of this regulation remains obscured because it has been difficult to observe in living cells. Here, we visualize the spatial organization and transcriptional outpu...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534382/ https://www.ncbi.nlm.nih.gov/pubmed/31124784 http://dx.doi.org/10.7554/eLife.41769 |