Strong CD8+ lymphocyte infiltration in combination with expression of HLA class I is associated with better tumor control in breast cancer patients treated with neoadjuvant chemotherapy

PURPOSE: Tumor-infiltrating lymphocytes (TILs) are associated with pathological complete response (pCR) and survival after neoadjuvant chemotherapy (NAC) in patients with early breast cancer. We investigated the prognostic and predictive role of TILs, macrophages, and HLA class 1 expression after NA...

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Detalles Bibliográficos
Autores principales: de Groot, A. F., Blok, E. J., Charehbili, A., Engels, C. C., Smit, V. T. H. B. M., Dekker-Ensink, N. G., Putter, H., Meershoek-Klein Kranenbarg, E., van de Velde, C. J. H., Liefers, G. J., Nortier, J. W. R., Kuppen, P. J. K., van der Burg, S. H., Kroep, J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534526/
https://www.ncbi.nlm.nih.gov/pubmed/30868392
http://dx.doi.org/10.1007/s10549-019-05195-y

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