Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors

Metastasis underlies the majority of cancer-related deaths yet remains poorly understood due, in part, to the lack of models in vivo. Here we show that expression of the EMT master inducer Snail in primary adult Drosophila intestinal tumors leads to the dissemination of tumor cells and formation of...

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Detalles Bibliográficos
Autores principales: Campbell, Kyra, Rossi, Fabrizio, Adams, Jamie, Pitsidianaki, Ioanna, Barriga, Francisco M., Garcia-Gerique, Laura, Batlle, Eduard, Casanova, Jordi, Casali, Andreu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534551/
https://www.ncbi.nlm.nih.gov/pubmed/31127094
http://dx.doi.org/10.1038/s41467-019-10269-y

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