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Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory
Encoding and retrieval of contextual memories is initially mediated by sparsely activated neurons, so-called engram cells, in the hippocampus. Subsequent memory persistence is thought to depend on network-wide changes involving progressive contribution of cortical regions, a process referred to as s...
Autores principales: | Matos, Mariana R., Visser, Esther, Kramvis, Ioannis, van der Loo, Rolinka J., Gebuis, Titia, Zalm, Robbert, Rao-Ruiz, Priyanka, Mansvelder, Huibert D., Smit, August B., van den Oever, Michel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534583/ https://www.ncbi.nlm.nih.gov/pubmed/31127098 http://dx.doi.org/10.1038/s41467-019-10266-1 |
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