Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy

Spinal muscular atrophy (SMA) is caused by loss-of-function mutations in the survival of motoneuron gene 1 (SMN1). SMA is characterized by motoneuron death, skeletal muscle denervation and atrophy. Disease severity inversely correlates with copy number of a second gene (SMN2), which harbors a splici...

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Detalles Bibliográficos
Autores principales: Rimer, Mendell, Seaberg, Bonnie L., Yen, Pei-Fen, Lam, Steven, Hastings, Robert Louis, Lee, Young il, Thompson, Wesley J., Feng, Zhihua, Metzger, Friedrich, Paushkin, Sergey, Ko, Chien-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534600/
https://www.ncbi.nlm.nih.gov/pubmed/31127156
http://dx.doi.org/10.1038/s41598-019-44222-2

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