Rational design of a hypoallergenic Phl p 7 variant for immunotherapy of polcalcin-sensitized patients

Polcalcins are important respiratory panallergens, whose IgE-binding capacity depends on the presence of calcium. Since specific immunotherapy is not yet available for the treatment of polcalcin-sensitized patients, we aimed to develop a molecule for efficient and safe immunotherapy. We generated a...

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Detalles Bibliográficos
Autores principales: Raith, Marianne, Zach, Doris, Sonnleitner, Linda, Woroszylo, Konrad, Focke-Tejkl, Margarete, Wank, Herbert, Graf, Thorsten, Kuehn, Annette, Pascal, Mariona, Muñoz-Cano, Rosa Maria, Wortmann, Judith, Aschauer, Philipp, Keller, Walter, Braeuer, Simone, Goessler, Walter, Swoboda, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534608/
https://www.ncbi.nlm.nih.gov/pubmed/31127132
http://dx.doi.org/10.1038/s41598-019-44208-0

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