Dissecting lung development and fibrosis at single-cell resolution

Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue c...

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Detalles Bibliográficos
Autores principales: Farber, Donna L., Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534905/
https://www.ncbi.nlm.nih.gov/pubmed/31126351
http://dx.doi.org/10.1186/s13073-019-0645-7
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author Farber, Donna L.
Sims, Peter A.
author_facet Farber, Donna L.
Sims, Peter A.
author_sort Farber, Donna L.
collection PubMed
description Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.
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spelling pubmed-65349052019-05-30 Dissecting lung development and fibrosis at single-cell resolution Farber, Donna L. Sims, Peter A. Genome Med Comment Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease. BioMed Central 2019-05-24 /pmc/articles/PMC6534905/ /pubmed/31126351 http://dx.doi.org/10.1186/s13073-019-0645-7 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Farber, Donna L.
Sims, Peter A.
Dissecting lung development and fibrosis at single-cell resolution
title Dissecting lung development and fibrosis at single-cell resolution
title_full Dissecting lung development and fibrosis at single-cell resolution
title_fullStr Dissecting lung development and fibrosis at single-cell resolution
title_full_unstemmed Dissecting lung development and fibrosis at single-cell resolution
title_short Dissecting lung development and fibrosis at single-cell resolution
title_sort dissecting lung development and fibrosis at single-cell resolution
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534905/
https://www.ncbi.nlm.nih.gov/pubmed/31126351
http://dx.doi.org/10.1186/s13073-019-0645-7
work_keys_str_mv AT farberdonnal dissectinglungdevelopmentandfibrosisatsinglecellresolution
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