Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide

BACKGROUND: Androgen receptor (AR) is expressed in approximately 70% of breast tumors. Recent studies increasingly support AR as a potential therapeutic target of AR-positive breast cancer. We have previously reported that deubiquitinase USP14 stabilizes AR proteins by deubiquitination and USP14 inh...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Xiaohong, Huang, Chuyi, Liao, Yuning, Liu, Yuan, He, Jinchan, Guo, Zhiqiang, Jiang, Lili, Wang, Xuejun, Liu, Jinbao, Huang, Hongbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534920/
https://www.ncbi.nlm.nih.gov/pubmed/31126320
http://dx.doi.org/10.1186/s13046-019-1227-7

Ejemplares similares

Ejemplares similares