Cargando…

Effects of Timolol Treatment on Pancreatic Antioxidant Enzymes in Streptozotocin-induced Diabetic Rats: An Experimental and Computational Study

BACKGROUND: The study aimed to investigate whether timolol-treatment has a beneficial effect on pentose phosphate pathway enzyme activities such as glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGDH) enzyme activities and cAMP level in streptozotocin-induced diabetic r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ulusu, Nuriye Nuray, Gok, Muslum, Erman, Burak, Turan, Belma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2019
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534949/ https://www.ncbi.nlm.nih.gov/pubmed/31156341 http://dx.doi.org/10.2478/jomb-2018-0034

Ejemplares similares

Antioxidant SMe1EC2 modulates pentose phosphate pathway and glutathione-dependent enzyme activities in tissues of aged diabetic rats
por: Ulusu, Nuray Nuriye, et al.
Publicado: (2017)

Data the DEHP induced changes on the trace element and mineral levels in the brain and testis tissues of rats
por: Aydemir, Duygu, et al.
Publicado: (2019)

Curious Cases of the Enzymes
por: Ulusu, Nuriye Nuray
Publicado: (2015)

Evolution of Enzyme Kinetic Mechanisms
por: Ulusu, Nuriye Nuray
Publicado: (2015)

The impact of the endocrine-disrupting chemicals on the glucose-6-phosphate dehydrogenase enzyme activity
por: Aydemir, Duygu, et al.
Publicado: (2023)

The possible importance of the antioxidants and oxidative stress metabolism in the emerging monkeypox disease: An opinion paper
por: Aydemir, Duygu, et al.
Publicado: (2022)

Correspondence: Angiotensin-converting enzyme 2 coated nanoparticles containing respiratory masks, chewing gums and nasal filters may be used for protection against COVID-19 infection
por: Aydemir, Duygu, et al.
Publicado: (2020)

Influence of Lifestyle Parameters – Dietary Habit, Chronic Stress and Environmental Factors, Jobs – on the Human Health in Relation to the COVID-19 Pandemic
por: Aydemir, Duygu, et al.
Publicado: (2020)

People with blood disorders can be more vulnerable during COVID-19 pandemic: A hypothesis paper
por: Aydemir, Duygu, et al.
Publicado: (2021)

The possible role of the endocrine disrupting chemicals on the premature and early menopause associated with the altered oxidative stress metabolism
por: Aydemir, Duygu, et al.
Publicado: (2023)

People having hematological disorders and hypercoagulability state need extra precautions because of the increased risk of thrombosis after COVID-19 vaccination
por: Aydemir, Duygu, et al.
Publicado: (2023)

ß-Blocker Timolol Prevents Arrhythmogenic Ca(2+) Release and Normalizes Ca(2+) and Zn(2+) Dyshomeostasis in Hyperglycemic Rat Heart
por: Tuncay, Erkan, et al.
Publicado: (2013)

Dataset of the analyzing trace elements and minerals via ICP-MS: Method validation for the mammalian tissue and serum samples
por: Aydemir, Duygu, et al.
Publicado: (2020)

Rosiglitazone-induced changes in the oxidative stress metabolism and fatty acid composition in relation with trace element status in the primary adipocytes
por: Aydemir, Duygu, et al.
Publicado: (2020)

Effects of the in-utero dicyclohexyl phthalate and di-n-hexyl phthalate administration on the oxidative stress-induced histopathological changes in the rat liver tissue correlated with serum biochemistry and hematological parameters
por: Aydemir, Duygu, et al.
Publicado: (2023)

Evaluation of Renal Function in Alzheimer’s Disease and Geriatric Patients: Results from a Turkish Two-center Study
por: Erbayraktar, Zubeyde, et al.
Publicado: (2017)

Evaluation of the Cell Behavior and Growth Characteristics of the Porcine Dermal Xenograft Patch in Relation to the Surface Properties
por: Aydemir, Duygu, et al.
Publicado: (2022)

Comparison of Spectrophotometric and Fluorimetric Methods in Evaluation of Biotinidase Deficiency
por: Işeri-Erten, Sevgin Özlem, et al.
Publicado: (2016)

Evaluation of the Hematological and Serum Biochemistry Parameters in the Pre-Symptomatic and Symptomatic Stages of ALS Disease to Support Early Diagnosis and Prognosis
por: Aydemir, Duygu, et al.
Publicado: (2022)

Impact of the Amyotrophic Lateral Sclerosis Disease on the Biomechanical Properties and Oxidative Stress Metabolism of the Lung Tissue Correlated With the Human Mutant SOD1(G93A) Protein Accumulation
por: Aydemir, Duygu, et al.
Publicado: (2022)

A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats
por: Durak, Aysegul, et al.
Publicado: (2018)

Mitochondria-Targeting Antioxidant Provides Cardioprotection through Regulation of Cytosolic and Mitochondrial Zn(2+) Levels with Re-Distribution of Zn(2+)-Transporters in Aged Rat Cardiomyocytes
por: Olgar, Yusuf, et al.
Publicado: (2019)

Effects of soybean isoflavone extract on the plasma lipid profiles and antioxidant enzyme activity in streptozotocin-induced diabetic rats
por: Shim, Jee-youn, et al.
Publicado: (2008)

Beneficial Antioxidative and Antiperoxidative Effect of Cinnamaldehyde Protect Streptozotocin-Induced Pancreatic β-Cells Damage in Wistar Rats
por: Subash-Babu, P., et al.
Publicado: (2014)

Changes in Oxidative Stress and Antioxidant Enzyme Activities in Streptozotocin-Induced Diabetes Mellitus in Rats: Role of Alhagi maurorum Extracts
por: Sheweita, S. A., et al.
Publicado: (2016)

Comparison of Latanoprost/Timolol with Carbonic Anhydrase Inhibitor and Dorzolamide/Timolol with Prostaglandin Analog in the Treatment of Glaucoma
por: Inoue, Kenji, et al.
Publicado: (2014)

Antiapoptotic and antioxidative effects of cerium oxide nanoparticles on the testicular tissues of streptozotocin-induced diabetic rats: An experimental study
por: Solgi, Torab, et al.
Publicado: (2021)

Effects of timolol maleate eye drops on experimentally dilated cardiomyopathy and healthy rabbits
por: Isaka, Mitsuhiro, et al.
Publicado: (2021)

Streptozotocin-induced diabetes mellitus affects lysosomal enzymes in rat liver
por: Peres, G.B., et al.
Publicado: (2014)

Antioxidant potential of theaflavin ameliorates the activities of key enzymes of glucose metabolism in high fat diet and streptozotocin – induced diabetic rats
por: Gothandam, Kirubananthan, et al.
Publicado: (2019)

Antioxidant potential of biflavonoid attenuates hyperglycemia by modulating the carbohydrate metabolic enzymes in high fat diet/streptozotocin induced diabetic rats
por: Ramalingam, Sundaram, et al.
Publicado: (2020)

Efficacy and safety of travoprost/timolol vs dorzolamide/timolol in patients with open-angle glaucoma or ocular hypertension
por: Teus, Miguel A, et al.
Publicado: (2009)

Brinzolamide/timolol versus dorzolamide/timolol fixed combinations: A hospital-based, prospective, randomized study
por: Galose, Mary S, et al.
Publicado: (2016)

Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats
por: Mohan, Yogesha, et al.
Publicado: (2013)

Treatment persistence and cost-effectiveness of latanoprost/latanoprost–timolol, bimatoprost/bimatoprost–timolol, and travoprost/travoprost–timolol in glaucoma: an analysis based on the United Kingdom general practitioner research database
por: Lafuma, Antoine, et al.
Publicado: (2011)

Timolol-induced interstitial lung disease
por: Patel, Hetain, et al.
Publicado: (2015)

Hyperkalemia due to topical timolol for hemangioma
por: Alasmari, Bushra, et al.
Publicado: (2023)

Modulation of Renal Insulin Signaling Pathway and Antioxidant Enzymes with Streptozotocin-Induced Diabetes: Effects of Resveratrol
por: Sadi, Gökhan, et al.
Publicado: (2018)

A comparative study on the efficacy, safety, and cost-effectiveness of bimatoprost/timolol and dorzolamide/timolol combinations in glaucoma patients
por: Jothi, R., et al.
Publicado: (2010)

Diurnal Intraocular Pressure with Bimatoprost/Timolol Fixed Combination versus Latanoprost/Timolol Fixed Combination in Healthy Subjects
por: Shim, Seong Hee, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_t68drmcrc4vvpathqfk03qulta