Cargando…

Remodeling of ER–plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca(2+) influx in mitosis

Store-operated Ca(2+) entry (SOCE), mediated by the endoplasmic reticulum (ER) Ca(2+) sensor stromal interaction molecule 1 (STIM1) and the plasma membrane (PM) channel Orai1, is inhibited during mitosis. STIM1 phosphorylation has been suggested to mediate this inhibition, but it is unclear whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Fang, Hubrack, Satanay Z., Chakraborty, Sumita, Sun, Lu, Alcantara-Adap, Ethel, Kulkarni, Rashmi, Billing, Anja M., Graumann, Johannes, Taylor, Colin W., Machaca, Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535005/
https://www.ncbi.nlm.nih.gov/pubmed/31064875
http://dx.doi.org/10.1073/pnas.1821399116

Ejemplares similares