Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract

Senescence is a leading cause of age-related cataract (ARC). The current study indicated that the senescence-associated protein, p53, total laminin (LM), LMα4, and transforming growth factor-beta1 (TGF-β1) in the cataractous anterior lens capsules (ALCs) increase with the grades of ARC. In cataracto...

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Detalles Bibliográficos
Autores principales: Yan, Yu, Yu, Haiyang, Sun, Liyao, Liu, Hanruo, Wang, Chao, Wei, Xi, Song, Fanqian, Li, Hulun, Ge, Hongyan, Qian, Hua, Li, Xiaoguang, Tang, Xianling, Liu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535067/
https://www.ncbi.nlm.nih.gov/pubmed/31076560
http://dx.doi.org/10.18632/aging.101943

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