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The role of ORMDL3/ATF6 in compensated beta cell proliferation during early diabetes

Endoplasmic reticulum (ER) stress in beta cells induces a signaling network called the unfolded protein response (UPR), which plays a dual role in diabetes. A key regulator of ER-stress and UPR, the orosomucoid 1-like protein 3 (ORMDL3), has been shown to regulate airway remodeling through a major U...

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Detalles Bibliográficos
Autores principales: Yang, Weixia, Sheng, Feifei, Sun, Baolan, Fischbach, Shane, Xiao, Xiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535075/
https://www.ncbi.nlm.nih.gov/pubmed/31061237
http://dx.doi.org/10.18632/aging.101949