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Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter

BACKGROUND: The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm...

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Autores principales: Bessow, Camila, Donato, Rafaela, de Souza, Tatiane, Chapon, Rita, Genro, Vanessa, Cunha-Filho, João Sabino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535188/
https://www.ncbi.nlm.nih.gov/pubmed/31128593
http://dx.doi.org/10.1186/s13048-019-0522-4
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author Bessow, Camila
Donato, Rafaela
de Souza, Tatiane
Chapon, Rita
Genro, Vanessa
Cunha-Filho, João Sabino
author_facet Bessow, Camila
Donato, Rafaela
de Souza, Tatiane
Chapon, Rita
Genro, Vanessa
Cunha-Filho, João Sabino
author_sort Bessow, Camila
collection PubMed
description BACKGROUND: The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm or AFC > 6: > 6 mm) of the follicular cohort could be a predictor for ovarian responsiveness, assessed by FORT, in a prospective cohort with 92 women with IVF indication, regular cycles and no abnormality in both ovaries. RESULTS: The mean age (±SD) of the women was 36.03 years (± 3.87 years), the median FORT was 43.30%. We found correlation between the FORT and AFC6 (r = − 0.237, P 0.023) but not between the FORT and AFC > 6 (r = − 0.055, P 0.602). CONCLUSIONS: The inverse correlation between FORT and AFC6 suggests that those follicles were less responsive to the exogenous FSH.
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spelling pubmed-65351882019-05-30 Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter Bessow, Camila Donato, Rafaela de Souza, Tatiane Chapon, Rita Genro, Vanessa Cunha-Filho, João Sabino J Ovarian Res Research BACKGROUND: The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm or AFC > 6: > 6 mm) of the follicular cohort could be a predictor for ovarian responsiveness, assessed by FORT, in a prospective cohort with 92 women with IVF indication, regular cycles and no abnormality in both ovaries. RESULTS: The mean age (±SD) of the women was 36.03 years (± 3.87 years), the median FORT was 43.30%. We found correlation between the FORT and AFC6 (r = − 0.237, P 0.023) but not between the FORT and AFC > 6 (r = − 0.055, P 0.602). CONCLUSIONS: The inverse correlation between FORT and AFC6 suggests that those follicles were less responsive to the exogenous FSH. BioMed Central 2019-05-25 /pmc/articles/PMC6535188/ /pubmed/31128593 http://dx.doi.org/10.1186/s13048-019-0522-4 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Bessow, Camila
Donato, Rafaela
de Souza, Tatiane
Chapon, Rita
Genro, Vanessa
Cunha-Filho, João Sabino
Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
title Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
title_full Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
title_fullStr Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
title_full_unstemmed Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
title_short Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
title_sort antral follicle responsiveness assessed by follicular output rate(fort) correlates with follicles diameter
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535188/
https://www.ncbi.nlm.nih.gov/pubmed/31128593
http://dx.doi.org/10.1186/s13048-019-0522-4
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