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Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter
BACKGROUND: The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535188/ https://www.ncbi.nlm.nih.gov/pubmed/31128593 http://dx.doi.org/10.1186/s13048-019-0522-4 |
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author | Bessow, Camila Donato, Rafaela de Souza, Tatiane Chapon, Rita Genro, Vanessa Cunha-Filho, João Sabino |
author_facet | Bessow, Camila Donato, Rafaela de Souza, Tatiane Chapon, Rita Genro, Vanessa Cunha-Filho, João Sabino |
author_sort | Bessow, Camila |
collection | PubMed |
description | BACKGROUND: The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm or AFC > 6: > 6 mm) of the follicular cohort could be a predictor for ovarian responsiveness, assessed by FORT, in a prospective cohort with 92 women with IVF indication, regular cycles and no abnormality in both ovaries. RESULTS: The mean age (±SD) of the women was 36.03 years (± 3.87 years), the median FORT was 43.30%. We found correlation between the FORT and AFC6 (r = − 0.237, P 0.023) but not between the FORT and AFC > 6 (r = − 0.055, P 0.602). CONCLUSIONS: The inverse correlation between FORT and AFC6 suggests that those follicles were less responsive to the exogenous FSH. |
format | Online Article Text |
id | pubmed-6535188 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-65351882019-05-30 Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter Bessow, Camila Donato, Rafaela de Souza, Tatiane Chapon, Rita Genro, Vanessa Cunha-Filho, João Sabino J Ovarian Res Research BACKGROUND: The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm or AFC > 6: > 6 mm) of the follicular cohort could be a predictor for ovarian responsiveness, assessed by FORT, in a prospective cohort with 92 women with IVF indication, regular cycles and no abnormality in both ovaries. RESULTS: The mean age (±SD) of the women was 36.03 years (± 3.87 years), the median FORT was 43.30%. We found correlation between the FORT and AFC6 (r = − 0.237, P 0.023) but not between the FORT and AFC > 6 (r = − 0.055, P 0.602). CONCLUSIONS: The inverse correlation between FORT and AFC6 suggests that those follicles were less responsive to the exogenous FSH. BioMed Central 2019-05-25 /pmc/articles/PMC6535188/ /pubmed/31128593 http://dx.doi.org/10.1186/s13048-019-0522-4 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Bessow, Camila Donato, Rafaela de Souza, Tatiane Chapon, Rita Genro, Vanessa Cunha-Filho, João Sabino Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter |
title | Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter |
title_full | Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter |
title_fullStr | Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter |
title_full_unstemmed | Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter |
title_short | Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter |
title_sort | antral follicle responsiveness assessed by follicular output rate(fort) correlates with follicles diameter |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535188/ https://www.ncbi.nlm.nih.gov/pubmed/31128593 http://dx.doi.org/10.1186/s13048-019-0522-4 |
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