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The mTORC1-autophagy pathway is a target for senescent cell elimination
Cellular senescence has recently been established as a key driver of organismal ageing. The state of senescence is controlled by extensive rewiring of signalling pathways, at the heart of which lies the mammalian Target of Rapamycin Complex I (mTORC1). Here we discuss recent publications aiming to e...
Autores principales: | Kucheryavenko, Olena, Nelson, Glyn, von Zglinicki, Thomas, Korolchuk, Viktor I., Carroll, Bernadette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535413/ https://www.ncbi.nlm.nih.gov/pubmed/30798505 http://dx.doi.org/10.1007/s10522-019-09802-9 |
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