Optimisation of a screening platform for determining IL-6 inflammatory signalling in the senescence-associated secretory phenotype (SASP)

Cellular senescence has been shown to be sufficient for the development of multiple age-related pathologies. Senescent cells adopt a secretory phenotype (the SASP) which comprises a large number of pro-inflammatory cytokines, chemokines and proteases. The SASP itself is thought to be causative in ma...

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Detalles Bibliográficos
Autores principales: Rolt, Adam, Nair, Anitha, Cox, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535418/
https://www.ncbi.nlm.nih.gov/pubmed/30741380
http://dx.doi.org/10.1007/s10522-019-09796-4

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