Cargando…
Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins
Cell senescence, a state of cell cycle arrest and altered metabolism with enhanced pro-inflammatory secretion, underlies at least some aspects of organismal ageing. The sirtuin family of deacetylases has been implicated in preventing premature ageing; sirtuin overexpression or resveratrol-mediated a...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535423/ https://www.ncbi.nlm.nih.gov/pubmed/30666570 http://dx.doi.org/10.1007/s10522-018-09792-0 |