Inhibition of vascular endothelial growth factor in young adult mice causes low bone blood flow and bone strength with no effect on bone mass in trabecular regions

OBJECTIVE: To determine the effect of an antibody to vascular endothelial growth factor (VEGF) on bone blood flow, bone strength, and bone mass in the young adult mouse. METHODS: Ten-week-old male BALB/cJ mice were body weight-randomized into either a rodent anti-VEGF monoclonal antibody (anti-VEGF,...

Descripción completa

Detalles Bibliográficos
Autores principales: Lane, N.E., Nyman, J.S., Uppuganti, S., Chaudhari, A.J., Aguirre, J.I., Shidara, K., Liu, X.P., Yao, W., Kimmel, D.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535464/
https://www.ncbi.nlm.nih.gov/pubmed/31193542
http://dx.doi.org/10.1016/j.bonr.2019.100210

Ejemplares similares

Ejemplares similares