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No Dose Adjustment for Isavuconazole Based on Age or Sex
This phase 1, open-label, single-dose, parallel-group study evaluated the pharmacokinetics (PK) of isavuconazole after a single oral dose of the prodrug isavuconazonium sulfate in healthy nonelderly (age, 18 to 45 years) and elderly (age, ≥65 years) males and females. Overall, 48 subjects were enrol...
Autores principales: | Desai, Amit V., Han, David, Kowalski, Donna L., Lademacher, Christopher, Pearlman, Helene, Yamazaki, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535513/ https://www.ncbi.nlm.nih.gov/pubmed/30962330 http://dx.doi.org/10.1128/AAC.02629-18 |
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