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Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors

Mycobacterium tuberculosis is the leading cause of morbidity and death resulting from infectious disease worldwide. The incredible disease burden, combined with the long course of drug treatment and an increasing incidence of antimicrobial resistance among M. tuberculosis isolates, necessitates nove...

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Detalles Bibliográficos
Autores principales: Berube, Bryan J., Russell, Dara, Castro, Lina, Choi, Seoung-ryoung, Narayanasamy, Prabagaran, Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535543/
https://www.ncbi.nlm.nih.gov/pubmed/30962346
http://dx.doi.org/10.1128/AAC.02661-18