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Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?

BACKGROUND AND OBJECTIVE: Chondroblastoma is difficult to treat as the tumor is surrounded by both articular cartilage and the epiphyseal plate. The differences in joint shape further complicate the problem. This retrospective study evaluates the efficacy of intraregional aggressive curettage and al...

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Autores principales: Liu, Qing, He, Hongbo, Yuan, Yuhao, Zeng, Hao, Long, Feng, Tian, Jian, Luo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535629/
https://www.ncbi.nlm.nih.gov/pubmed/31193486
http://dx.doi.org/10.1016/j.jbo.2019.100240
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author Liu, Qing
He, Hongbo
Yuan, Yuhao
Zeng, Hao
Long, Feng
Tian, Jian
Luo, Wei
author_facet Liu, Qing
He, Hongbo
Yuan, Yuhao
Zeng, Hao
Long, Feng
Tian, Jian
Luo, Wei
author_sort Liu, Qing
collection PubMed
description BACKGROUND AND OBJECTIVE: Chondroblastoma is difficult to treat as the tumor is surrounded by both articular cartilage and the epiphyseal plate. The differences in joint shape further complicate the problem. This retrospective study evaluates the efficacy of intraregional aggressive curettage and allogeneic bone grafting for treating chondroblastoma of the adjoining knee joint. METHODS: From February 2010 to February 2017, 36 patients with chondroblastoma of the adjoining knee joint were identified. All patients were treated with intraregional aggressive curettage, phenolization, and allogeneic bone grafting. Follow-up for lesion healing, local recurrence, functional outcomes and secondary osteoarthritis were assessed both clinically and radiologically. RESULTS: Thirty-six patients (mean age 17 years) were enrolled with a mean follow-up of 51.8 months (18–98 months). The tumor locations were as follows: distal femur (14), proximal tibia (20), and patella (2). Only 1 patient relapsed, 10 months post-operation. All patients had good bone healing. No knee varus or valgus deformity developed. The mean Musculoskeletal Tumor Society functional score was 28.6 ± 1.1 post-operation. At the last follow-up, secondary osteoarthritis was found in 1 patient, the patient was asymptomatic. CONCLUSIONS: Intraregional aggressive curettage, phenolization, and allogeneic bone grafting are effective for treatment of chondroblastoma of the adjoining knee joint.
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spelling pubmed-65356292019-05-30 Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated? Liu, Qing He, Hongbo Yuan, Yuhao Zeng, Hao Long, Feng Tian, Jian Luo, Wei J Bone Oncol Research Article BACKGROUND AND OBJECTIVE: Chondroblastoma is difficult to treat as the tumor is surrounded by both articular cartilage and the epiphyseal plate. The differences in joint shape further complicate the problem. This retrospective study evaluates the efficacy of intraregional aggressive curettage and allogeneic bone grafting for treating chondroblastoma of the adjoining knee joint. METHODS: From February 2010 to February 2017, 36 patients with chondroblastoma of the adjoining knee joint were identified. All patients were treated with intraregional aggressive curettage, phenolization, and allogeneic bone grafting. Follow-up for lesion healing, local recurrence, functional outcomes and secondary osteoarthritis were assessed both clinically and radiologically. RESULTS: Thirty-six patients (mean age 17 years) were enrolled with a mean follow-up of 51.8 months (18–98 months). The tumor locations were as follows: distal femur (14), proximal tibia (20), and patella (2). Only 1 patient relapsed, 10 months post-operation. All patients had good bone healing. No knee varus or valgus deformity developed. The mean Musculoskeletal Tumor Society functional score was 28.6 ± 1.1 post-operation. At the last follow-up, secondary osteoarthritis was found in 1 patient, the patient was asymptomatic. CONCLUSIONS: Intraregional aggressive curettage, phenolization, and allogeneic bone grafting are effective for treatment of chondroblastoma of the adjoining knee joint. Elsevier 2019-05-13 /pmc/articles/PMC6535629/ /pubmed/31193486 http://dx.doi.org/10.1016/j.jbo.2019.100240 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Liu, Qing
He, Hongbo
Yuan, Yuhao
Zeng, Hao
Long, Feng
Tian, Jian
Luo, Wei
Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
title Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
title_full Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
title_fullStr Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
title_full_unstemmed Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
title_short Have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
title_sort have the difficulties and complications of surgical treatment for chondroblastoma of the adjoining knee joint been overestimated?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535629/
https://www.ncbi.nlm.nih.gov/pubmed/31193486
http://dx.doi.org/10.1016/j.jbo.2019.100240
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