Bioequivalence of paclitaxel protein-bound particles in patients with breast cancer: determining total and unbound paclitaxel in plasma by rapid equilibrium dialysis and liquid chromatography–tandem mass spectrometry

Background and objective: Paclitaxel protein-bound particles for injectable suspension (nab-paclitaxel) showed many advantages in safety, effectiveness, and convenience. Different from conventional formulations, the bioequivalence evaluation of nab-paclitaxel formulations requires to determine the t...

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Detalles Bibliográficos
Autores principales: Li, Junling, Li, Wei, Dai, Xiaojian, Zhong, Dafang, Ding, Yaping, Chen, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535670/
https://www.ncbi.nlm.nih.gov/pubmed/31190752
http://dx.doi.org/10.2147/DDDT.S200679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535670/
https://www.ncbi.nlm.nih.gov/pubmed/31190752
http://dx.doi.org/10.2147/DDDT.S200679

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