Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial()

BACKGROUND: Pharmacokinetic (PK) and pharmacodynamic (PD) data on perioperative antibiotic prophylaxis or antibiotic therapy are rare in patients suffering from morbid obesity. Furthermore, dosing regimens should be based on PK/PD models that ensure effective antibiotic exposure not in plasma, but p...

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Detalles Bibliográficos
Autores principales: Simon, P., Petroff, D., Dorn, C., Ehmann, L., Kloft, C., Prettin, C., Dietrich, A., Zeitlinger, M., Kees, F., Wrigge, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535681/
https://www.ncbi.nlm.nih.gov/pubmed/31193565
http://dx.doi.org/10.1016/j.conctc.2019.100375

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