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Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy

Metformin is a widely used antidiabetic drug for type 2 diabetes that can play a cardioprotective role through multiple pathways. It is a recognized agonist of AMP-activated protein kinase (AMPK) that blocks mitochondrial complex I. The NLRP3 inflammasome has been demonstrated to be activated in dia...

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Detalles Bibliográficos
Autores principales:	Yang, Fan, Qin, Ying, Wang, Yueqiu, Meng, Songyan, Xian, Huimin, Che, Hui, Lv, Jie, Li, Yang, Yu, Yahan, Bai, Yunlong, Wang, Lihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535781/ https://www.ncbi.nlm.nih.gov/pubmed/31182921 http://dx.doi.org/10.7150/ijbs.29680

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