Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression

Pancreatic ductal adenocarcinoma (PDAC) has unique microenvironment with extensive infiltration of fibroblasts, which are mainly derived from the resident pancreatic stellate cells (PaSCs). As activated PaSCs constitute a major contributor to pancreatic cancer progression, the mechanisms underlying...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Chuxiao, Tu, Chaoyong, Cheng, Xiangdong, Xu, Zhiyuan, Wang, Xiaoguang, Shen, Jian, Chai, Kequn, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784/
https://www.ncbi.nlm.nih.gov/pubmed/31182922
http://dx.doi.org/10.7150/ijbs.27825

Ejemplares similares

Ejemplares similares