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Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy

OBJECTIVE: Hypoxia is central in the pathogenesis of diabetic retinopathy (DR). Hypoxia-inducible factor-1 (HIF-1) is the key mediator in cellular oxygen homeostasis that facilitates the adaptation to hypoxia. HIF-1 is repressed by hyperglycemia contributing by this to the development of complicatio...

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Detalles Bibliográficos
Autores principales:	Ekberg, Neda Rajamand, Eliasson, Sofie, Li, Young Wen, Zheng, Xiaowei, Chatzidionysiou, Katerina, Falhammar, Henrik, Gu, Harvest F., Catrina, Sergiu-Bogdan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535890/ https://www.ncbi.nlm.nih.gov/pubmed/31214621 http://dx.doi.org/10.1155/2019/2936962

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