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Pro-Apoptotic Effects of Estetrol on Long-Term Estrogen-Deprived Breast Cancer Cells and at Low Doses on Hormone-Sensitive Cells
PURPOSE: Postmenopausal women with estrogen receptor-positive breast cancers often respond initially to tamoxifen or aromatase inhibitor therapy. Resistance to these treatments usually develops within 12 to 18 months. Clinical studies have demonstrated that high-dose estrogen can induce regression o...
Autores principales: | Yue, Wei, Verhoeven, Carole, Bernnink, Herjan Coelingh, Wang, Ji-ping, Santen, Richard J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535901/ https://www.ncbi.nlm.nih.gov/pubmed/31205415 http://dx.doi.org/10.1177/1178223419844198 |
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