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Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absen...

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Autores principales: Karthikeyan, Kamalesh, Balla, Sudarshan, Alpert, Martin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536155/
https://www.ncbi.nlm.nih.gov/pubmed/31092487
http://dx.doi.org/10.1136/bcr-2018-225947
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author Karthikeyan, Kamalesh
Balla, Sudarshan
Alpert, Martin A
author_facet Karthikeyan, Kamalesh
Balla, Sudarshan
Alpert, Martin A
author_sort Karthikeyan, Kamalesh
collection PubMed
description Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absence of antineutrophil cytoplasmic antibodies. Cardiac complications include coronary arteritis (rare), pericarditis, myocarditis, endocardial fibrosis (Loeffler’s endocarditis) and intracavitary thrombosis of the left or right ventricle. This is the first reported case of large non-infectious valvular vegetations associated with EGPA.
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spelling pubmed-65361552019-06-12 Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis Karthikeyan, Kamalesh Balla, Sudarshan Alpert, Martin A BMJ Case Rep Rare Disease Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absence of antineutrophil cytoplasmic antibodies. Cardiac complications include coronary arteritis (rare), pericarditis, myocarditis, endocardial fibrosis (Loeffler’s endocarditis) and intracavitary thrombosis of the left or right ventricle. This is the first reported case of large non-infectious valvular vegetations associated with EGPA. BMJ Publishing Group 2019-05-14 /pmc/articles/PMC6536155/ /pubmed/31092487 http://dx.doi.org/10.1136/bcr-2018-225947 Text en © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Rare Disease
Karthikeyan, Kamalesh
Balla, Sudarshan
Alpert, Martin A
Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
title Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
title_full Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
title_fullStr Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
title_full_unstemmed Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
title_short Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
title_sort non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
topic Rare Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536155/
https://www.ncbi.nlm.nih.gov/pubmed/31092487
http://dx.doi.org/10.1136/bcr-2018-225947
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