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Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absen...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536155/ https://www.ncbi.nlm.nih.gov/pubmed/31092487 http://dx.doi.org/10.1136/bcr-2018-225947 |
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author | Karthikeyan, Kamalesh Balla, Sudarshan Alpert, Martin A |
author_facet | Karthikeyan, Kamalesh Balla, Sudarshan Alpert, Martin A |
author_sort | Karthikeyan, Kamalesh |
collection | PubMed |
description | Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absence of antineutrophil cytoplasmic antibodies. Cardiac complications include coronary arteritis (rare), pericarditis, myocarditis, endocardial fibrosis (Loeffler’s endocarditis) and intracavitary thrombosis of the left or right ventricle. This is the first reported case of large non-infectious valvular vegetations associated with EGPA. |
format | Online Article Text |
id | pubmed-6536155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-65361552019-06-12 Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis Karthikeyan, Kamalesh Balla, Sudarshan Alpert, Martin A BMJ Case Rep Rare Disease Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absence of antineutrophil cytoplasmic antibodies. Cardiac complications include coronary arteritis (rare), pericarditis, myocarditis, endocardial fibrosis (Loeffler’s endocarditis) and intracavitary thrombosis of the left or right ventricle. This is the first reported case of large non-infectious valvular vegetations associated with EGPA. BMJ Publishing Group 2019-05-14 /pmc/articles/PMC6536155/ /pubmed/31092487 http://dx.doi.org/10.1136/bcr-2018-225947 Text en © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Rare Disease Karthikeyan, Kamalesh Balla, Sudarshan Alpert, Martin A Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
title | Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
title_full | Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
title_fullStr | Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
title_full_unstemmed | Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
title_short | Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
title_sort | non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis |
topic | Rare Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536155/ https://www.ncbi.nlm.nih.gov/pubmed/31092487 http://dx.doi.org/10.1136/bcr-2018-225947 |
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