Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis

We report the case of a 6-year-old girl with juvenile idiopathic arthritis and anterior uveitis who was treated with two doses of intravenous methylprednisolone for acute arthritis. She developed severe ocular hypertension (intraocular pressures (IOPs) of 54 mm Hg in the right eye and 61 mm Hg in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Beverstock, Andrew, Kelly, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536218/
https://www.ncbi.nlm.nih.gov/pubmed/31129643
http://dx.doi.org/10.1136/bcr-2019-229803
_version_ 1783421716597309440
author Beverstock, Andrew
Kelly, Alison
author_facet Beverstock, Andrew
Kelly, Alison
author_sort Beverstock, Andrew
collection PubMed
description We report the case of a 6-year-old girl with juvenile idiopathic arthritis and anterior uveitis who was treated with two doses of intravenous methylprednisolone for acute arthritis. She developed severe ocular hypertension (intraocular pressures (IOPs) of 54 mm Hg in the right eye and 61 mm Hg in the left eye) requiring inpatient therapy with intravenous acetazolamide. The normal range of values for IOP is 12–22 mm Hg. This severe case of acute intraocular hypertension due to systemic steroids highlights the need to consider monitoring of IOPs for children on high-dose topical and systemic steroids with risk factors for raised IOP.
format Online
Article
Text
id pubmed-6536218
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-65362182019-06-12 Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis Beverstock, Andrew Kelly, Alison BMJ Case Rep Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions We report the case of a 6-year-old girl with juvenile idiopathic arthritis and anterior uveitis who was treated with two doses of intravenous methylprednisolone for acute arthritis. She developed severe ocular hypertension (intraocular pressures (IOPs) of 54 mm Hg in the right eye and 61 mm Hg in the left eye) requiring inpatient therapy with intravenous acetazolamide. The normal range of values for IOP is 12–22 mm Hg. This severe case of acute intraocular hypertension due to systemic steroids highlights the need to consider monitoring of IOPs for children on high-dose topical and systemic steroids with risk factors for raised IOP. BMJ Publishing Group 2019-05-24 /pmc/articles/PMC6536218/ /pubmed/31129643 http://dx.doi.org/10.1136/bcr-2019-229803 Text en © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
Beverstock, Andrew
Kelly, Alison
Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
title Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
title_full Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
title_fullStr Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
title_full_unstemmed Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
title_short Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
title_sort severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
topic Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536218/
https://www.ncbi.nlm.nih.gov/pubmed/31129643
http://dx.doi.org/10.1136/bcr-2019-229803
work_keys_str_mv AT beverstockandrew severeacuteocularhypertensionfollowingpulsedmethylprednisoloneforjuvenileidiopathicarthritis
AT kellyalison severeacuteocularhypertensionfollowingpulsedmethylprednisoloneforjuvenileidiopathicarthritis

Ejemplares similares