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Enhanced metabolic activities for ATP production and elevated metabolic flux via pentose phosphate pathway contribute for better CIK cells expansion
OBJECTIVE: Ex vivo expansion is an effective way to produce cytokine‐induced killer (CIK) cells needed for clinical trials. Here, ex vivo expansion and metabolism characters of CIK cells in static and dynamic cultures and the relationship between cell expansion and metabolism were investigated. MATE...
Autores principales: | Zhang, Weiwei, Huang, Huimin, Cai, Haibo, Tan, Wen‐Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536417/ https://www.ncbi.nlm.nih.gov/pubmed/30847992 http://dx.doi.org/10.1111/cpr.12594 |
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