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Recent Advances in Biosensors for Nucleic Acid and Exosome Detection
Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied in diverse fields such as clinical monitoring, in vi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chonnam National University Medical School
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536430/ https://www.ncbi.nlm.nih.gov/pubmed/31161120 http://dx.doi.org/10.4068/cmj.2019.55.2.86 |
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author | Fu, Zirui Lu, Yi-Cheng Lai, James J. |
author_facet | Fu, Zirui Lu, Yi-Cheng Lai, James J. |
author_sort | Fu, Zirui |
collection | PubMed |
description | Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied in diverse fields such as clinical monitoring, in vitro diagnostics, food industry etc. Based on signal transduction mechanisms, biosensors can be categorized into three major types: optical biosensors, electrochemical biosensors, and mass-based biosensors. Recently, the need for faster, more sensitive detection of biomolecules has compeled researchers to develop various sensing techniques. In this review, the basic structure and sensing principles of biosensors are introduced. Additionally, the review discusses multiple recent works about nucleic acid and exosome sensing. |
format | Online Article Text |
id | pubmed-6536430 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Chonnam National University Medical School |
record_format | MEDLINE/PubMed |
spelling | pubmed-65364302019-06-03 Recent Advances in Biosensors for Nucleic Acid and Exosome Detection Fu, Zirui Lu, Yi-Cheng Lai, James J. Chonnam Med J Review Article Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied in diverse fields such as clinical monitoring, in vitro diagnostics, food industry etc. Based on signal transduction mechanisms, biosensors can be categorized into three major types: optical biosensors, electrochemical biosensors, and mass-based biosensors. Recently, the need for faster, more sensitive detection of biomolecules has compeled researchers to develop various sensing techniques. In this review, the basic structure and sensing principles of biosensors are introduced. Additionally, the review discusses multiple recent works about nucleic acid and exosome sensing. Chonnam National University Medical School 2019-05 2019-05-23 /pmc/articles/PMC6536430/ /pubmed/31161120 http://dx.doi.org/10.4068/cmj.2019.55.2.86 Text en © Chonnam Medical Journal, 2019 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Fu, Zirui Lu, Yi-Cheng Lai, James J. Recent Advances in Biosensors for Nucleic Acid and Exosome Detection |
title | Recent Advances in Biosensors for Nucleic Acid and Exosome Detection |
title_full | Recent Advances in Biosensors for Nucleic Acid and Exosome Detection |
title_fullStr | Recent Advances in Biosensors for Nucleic Acid and Exosome Detection |
title_full_unstemmed | Recent Advances in Biosensors for Nucleic Acid and Exosome Detection |
title_short | Recent Advances in Biosensors for Nucleic Acid and Exosome Detection |
title_sort | recent advances in biosensors for nucleic acid and exosome detection |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536430/ https://www.ncbi.nlm.nih.gov/pubmed/31161120 http://dx.doi.org/10.4068/cmj.2019.55.2.86 |
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