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Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population

Quality of life is affected by factors such as regional differences in access to treatment choices, and rehabilitation. This study aims to assess the result of epilepsy surgery and its impact on QoL in Iran. The data for 60 patients who underwent epilepsy surgery in Loghman-Hakim hospital between 20...

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Autores principales: Lotfinia, Mahmoud, Maloumeh, Ehsan Nazari, Asaadi, Sina, Omidbeigi, Mahmoud, Sharifi, Guive, Asadi, Bahador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536509/
https://www.ncbi.nlm.nih.gov/pubmed/31133687
http://dx.doi.org/10.1038/s41598-019-44442-6
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author Lotfinia, Mahmoud
Maloumeh, Ehsan Nazari
Asaadi, Sina
Omidbeigi, Mahmoud
Sharifi, Guive
Asadi, Bahador
author_facet Lotfinia, Mahmoud
Maloumeh, Ehsan Nazari
Asaadi, Sina
Omidbeigi, Mahmoud
Sharifi, Guive
Asadi, Bahador
author_sort Lotfinia, Mahmoud
collection PubMed
description Quality of life is affected by factors such as regional differences in access to treatment choices, and rehabilitation. This study aims to assess the result of epilepsy surgery and its impact on QoL in Iran. The data for 60 patients who underwent epilepsy surgery in Loghman-Hakim hospital between 2003 to 2017 were analyzed prospectively through clinical observation. Clinical variables of interest and the WHOQOL-BREF scale to assess QoL were applied. Scores of operated patients were compared to their preoperative scores as well as epileptic patients controlled with antiepileptic drugs (AEDs) and healthy individuals. The mean age of surgery group patients was 33.78 (34 male; 26 female). Twenty seven patients underwent temporal mesial lobectomy, 20 anterior callosotomy, and 13 neocortical resections. The average QoL score in healthy group was 72.48, in AEDs controls was 56.16, and in operated patients was 65.61. In addition, analysis showed a significant increase in postoperative QoL of the surgical group compared to the AEDs controls. Epilepsy surgery could be the best approach in patients suffering from drug-resistant epilepsy even in developing countries, which can result in seizure relief and a reduction in the frequency of disabling seizures.
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spelling pubmed-65365092019-06-06 Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population Lotfinia, Mahmoud Maloumeh, Ehsan Nazari Asaadi, Sina Omidbeigi, Mahmoud Sharifi, Guive Asadi, Bahador Sci Rep Article Quality of life is affected by factors such as regional differences in access to treatment choices, and rehabilitation. This study aims to assess the result of epilepsy surgery and its impact on QoL in Iran. The data for 60 patients who underwent epilepsy surgery in Loghman-Hakim hospital between 2003 to 2017 were analyzed prospectively through clinical observation. Clinical variables of interest and the WHOQOL-BREF scale to assess QoL were applied. Scores of operated patients were compared to their preoperative scores as well as epileptic patients controlled with antiepileptic drugs (AEDs) and healthy individuals. The mean age of surgery group patients was 33.78 (34 male; 26 female). Twenty seven patients underwent temporal mesial lobectomy, 20 anterior callosotomy, and 13 neocortical resections. The average QoL score in healthy group was 72.48, in AEDs controls was 56.16, and in operated patients was 65.61. In addition, analysis showed a significant increase in postoperative QoL of the surgical group compared to the AEDs controls. Epilepsy surgery could be the best approach in patients suffering from drug-resistant epilepsy even in developing countries, which can result in seizure relief and a reduction in the frequency of disabling seizures. Nature Publishing Group UK 2019-05-27 /pmc/articles/PMC6536509/ /pubmed/31133687 http://dx.doi.org/10.1038/s41598-019-44442-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lotfinia, Mahmoud
Maloumeh, Ehsan Nazari
Asaadi, Sina
Omidbeigi, Mahmoud
Sharifi, Guive
Asadi, Bahador
Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population
title Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population
title_full Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population
title_fullStr Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population
title_full_unstemmed Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population
title_short Health-related quality of life after epilepsy surgery: A prospective, controlled follow-up on the Iranian population
title_sort health-related quality of life after epilepsy surgery: a prospective, controlled follow-up on the iranian population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536509/
https://www.ncbi.nlm.nih.gov/pubmed/31133687
http://dx.doi.org/10.1038/s41598-019-44442-6
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