Cargando…

Upregulation of the NLRC4 inflammasome contributes to poor prognosis in glioma patients

Inflammation in tumor microenvironments is implicated in the pathogenesis of tumor development. In particular, inflammasomes, which modulate innate immune functions, are linked to tumor growth and anticancer responses. However, the role of the NLRC4 inflammasome in gliomas remains unclear. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Jaejoon, Kim, Min Jun, Park, YoungJoon, Ahn, Ju Won, Hwang, So Jung, Moon, Jong-Seok, Cho, Kyung Gi, Kwack, KyuBum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536517/ https://www.ncbi.nlm.nih.gov/pubmed/31133717 http://dx.doi.org/10.1038/s41598-019-44261-9

Ejemplares similares

CeRNA Network Analysis Representing Characteristics of Different Tumor Environments Based on 1p/19q Codeletion in Oligodendrogliomas
por: Ahn, Ju Won, et al.
Publicado: (2020)

Correction: Ahn, J.W., et al. CeRNA Network Analysis Representing Characteristics of Different Tumor Environments Based on 1p/19q Codeletion in Oligodendrogliomas. Cancers 2020, 12, 2543
por: Ahn, Ju Won, et al.
Publicado: (2021)

Association of Tim-3/Gal-9 Axis with NLRC4 Inflammasome in Glioma Malignancy: Tim-3/Gal-9 Induce the NLRC4 Inflammasome
por: Sim, JeongMin, et al.
Publicado: (2022)

Dysregulation of inflammasome activation in glioma
por: Sim, JeongMin, et al.
Publicado: (2023)

Autologous adoptive immune-cell therapy elicited a durable response with enhanced immune reaction signatures in patients with recurrent glioblastoma: An open label, phase I/IIa trial
por: Lim, Jaejoon, et al.
Publicado: (2021)

Identification of potential causal variants for premature ovarian failure by whole exome sequencing
por: Jin, Haengun, et al.
Publicado: (2020)

Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy
por: Yuan, Fang, et al.
Publicado: (2016)

Emerging Concepts about NAIP/NLRC4 Inflammasomes
por: Lage, Silvia Lucena, et al.
Publicado: (2014)

Advances in Understanding Activation and Function of the NLRC4 Inflammasome
por: Sundaram, Balamurugan, et al.
Publicado: (2021)

NLRC4 Inflammasome-Mediated Regulation of Eosinophilic Functions
por: Akkaya, Ilgin, et al.
Publicado: (2021)

Interaction between thyroglobulin and ADAMTS16 in premature ovarian failure
por: Pyun, Jung-A, et al.
Publicado: (2014)

Down with doublespeak: NAIP/NLRC4 inflammasomes get specific
por: Aachoui, Youssef, et al.
Publicado: (2016)

A role for the NLRC4 inflammasome in premature rupture of membrane
por: Zhu, Jinming, et al.
Publicado: (2020)

Clostridioides difficile Flagellin Activates the Intracellular NLRC4 Inflammasome
por: Chebly, Hiba, et al.
Publicado: (2022)

Correlation of microrna-372 upregulation with poor prognosis in human glioma
por: Li, Gang, et al.
Publicado: (2013)

Transcriptomic Landscape of Lower Grade Glioma Based on Age-Related Non-Silent Somatic Mutations
por: Park, YoungJoon, et al.
Publicado: (2021)

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
por: Sutterwala, Fayyaz S., et al.
Publicado: (2007)

The NLRC4 inflammasome requires IRF8-dependent production of NAIPs
por: Lee, Ein, et al.
Publicado: (2018)

SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation
por: Guan, Chenyang, et al.
Publicado: (2021)

Updating the NLRC4 Inflammasome: from Bacterial Infections to Autoimmunity and Cancer
por: Wen, Jiexia, et al.
Publicado: (2021)

Gonadal Hormones E2 and P Mitigate Cerebral Ischemia-Induced Upregulation of the AIM2 and NLRC4 Inflammasomes in Rats
por: Habib, Pardes, et al.
Publicado: (2020)

A Disintegrin and Metalloproteinase 9 (ADAM9) in Advanced Hepatocellular Carcinoma and Their Role as a Biomarker During Hepatocellular Carcinoma Immunotherapy
por: Oh, Sooyeon, et al.
Publicado: (2020)

Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling
por: Yang, Jungmin, et al.
Publicado: (2020)

Association of an APBA3 Missense Variant with Risk of Premature Ovarian Failure in the Korean Female Population
por: Park, JeongMan, et al.
Publicado: (2020)

Nitric oxide synthase Type II expression by different cell types in MHV-JHM encephalitis suggests distinct roles for nitric oxide in acute versus persistent virus infection
por: Grzybicki, Dana M, et al.
Publicado: (1997)

Natural Killer Cell Therapy: A New Treatment Paradigm for Solid Tumors
por: Oh, Sooyeon, et al.
Publicado: (2019)

Downregulation of LOC441461 Promotes Cell Growth and Motility in Human Gastric Cancer
por: Lee, Sang-soo, et al.
Publicado: (2022)

Obesity-associated NLRC4 inflammasome activation drives breast cancer progression
por: Kolb, Ryan, et al.
Publicado: (2016)

Discovery and characterization of small-molecule inhibitors of NLRP3 and NLRC4 inflammasomes
por: Sebastian-Valverde, Maria, et al.
Publicado: (2021)

The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats
por: Gan, Hui, et al.
Publicado: (2021)

Expression and clinical value of NLRP1 and NLRC4 inflammasomes in prostate cancer
por: Liang, Ke, et al.
Publicado: (2023)

Protocol for reconstitution of oligomeric assembly of NAIP5-NLRC4 inflammasome in vitro
por: Wu, Xiurong, et al.
Publicado: (2023)

Maximal surgical resection and adjuvant surgical technique to prolong the survival of adult patients with thalamic glioblastoma
por: Lim, Jaejoon, et al.
Publicado: (2021)

Comparing the Expression of Canonical and Non-Canonical Inflammasomes Across Glioma Grades: Evaluating Their Potential as an Aggressiveness Marker
por: Kim, Yu Jin, et al.
Publicado: (2023)

Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation
por: Ahn, Huijeong, et al.
Publicado: (2017)

Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes
por: Kim, Changshin, et al.
Publicado: (2018)

Role of RGMc as a Neogenin Ligand in Follicular Development in the Ovary
por: Kim, Yu Jin, et al.
Publicado: (2021)

Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease
por: Huang, Ying-Hsien, et al.
Publicado: (2018)

Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection
por: Akhter, Anwari, et al.
Publicado: (2009)

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
por: Canna, Scott W., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hoqm0i6bjbfmfnshtvd85s923g