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Optimal integration of intraneural somatosensory feedback with visual information: a single-case study

Providing somatosensory feedback to amputees is a long-standing objective in prosthesis research. Recently, implantable neural interfaces have yielded promising results in this direction. There is now considerable evidence that the nervous system integrates redundant signals optimally, weighting eac...

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Autores principales: Risso, G., Valle, G., Iberite, F., Strauss, I., Stieglitz, T., Controzzi, M., Clemente, F., Granata, G., Rossini, P. M., Micera, S., Baud-Bovy, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536542/
https://www.ncbi.nlm.nih.gov/pubmed/31133637
http://dx.doi.org/10.1038/s41598-019-43815-1
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author Risso, G.
Valle, G.
Iberite, F.
Strauss, I.
Stieglitz, T.
Controzzi, M.
Clemente, F.
Granata, G.
Rossini, P. M.
Micera, S.
Baud-Bovy, G.
author_facet Risso, G.
Valle, G.
Iberite, F.
Strauss, I.
Stieglitz, T.
Controzzi, M.
Clemente, F.
Granata, G.
Rossini, P. M.
Micera, S.
Baud-Bovy, G.
author_sort Risso, G.
collection PubMed
description Providing somatosensory feedback to amputees is a long-standing objective in prosthesis research. Recently, implantable neural interfaces have yielded promising results in this direction. There is now considerable evidence that the nervous system integrates redundant signals optimally, weighting each signal according to its reliability. One question of interest is whether artificial sensory feedback is combined with other sensory information in a natural manner. In this single-case study, we show that an amputee with a bidirectional prosthesis integrated artificial somatosensory feedback and blurred visual information in a statistically optimal fashion when estimating the size of a hand-held object. The patient controlled the opening and closing of the prosthetic hand through surface electromyography, and received intraneural stimulation proportional to the object’s size in the ulnar nerve when closing the robotic hand on the object. The intraneural stimulation elicited a vibration sensation in the phantom hand that substituted the missing haptic feedback. This result indicates that sensory substitution based on intraneural feedback can be integrated with visual feedback and make way for a promising method to investigate multimodal integration processes.
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spelling pubmed-65365422019-06-06 Optimal integration of intraneural somatosensory feedback with visual information: a single-case study Risso, G. Valle, G. Iberite, F. Strauss, I. Stieglitz, T. Controzzi, M. Clemente, F. Granata, G. Rossini, P. M. Micera, S. Baud-Bovy, G. Sci Rep Article Providing somatosensory feedback to amputees is a long-standing objective in prosthesis research. Recently, implantable neural interfaces have yielded promising results in this direction. There is now considerable evidence that the nervous system integrates redundant signals optimally, weighting each signal according to its reliability. One question of interest is whether artificial sensory feedback is combined with other sensory information in a natural manner. In this single-case study, we show that an amputee with a bidirectional prosthesis integrated artificial somatosensory feedback and blurred visual information in a statistically optimal fashion when estimating the size of a hand-held object. The patient controlled the opening and closing of the prosthetic hand through surface electromyography, and received intraneural stimulation proportional to the object’s size in the ulnar nerve when closing the robotic hand on the object. The intraneural stimulation elicited a vibration sensation in the phantom hand that substituted the missing haptic feedback. This result indicates that sensory substitution based on intraneural feedback can be integrated with visual feedback and make way for a promising method to investigate multimodal integration processes. Nature Publishing Group UK 2019-05-27 /pmc/articles/PMC6536542/ /pubmed/31133637 http://dx.doi.org/10.1038/s41598-019-43815-1 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Risso, G.
Valle, G.
Iberite, F.
Strauss, I.
Stieglitz, T.
Controzzi, M.
Clemente, F.
Granata, G.
Rossini, P. M.
Micera, S.
Baud-Bovy, G.
Optimal integration of intraneural somatosensory feedback with visual information: a single-case study
title Optimal integration of intraneural somatosensory feedback with visual information: a single-case study
title_full Optimal integration of intraneural somatosensory feedback with visual information: a single-case study
title_fullStr Optimal integration of intraneural somatosensory feedback with visual information: a single-case study
title_full_unstemmed Optimal integration of intraneural somatosensory feedback with visual information: a single-case study
title_short Optimal integration of intraneural somatosensory feedback with visual information: a single-case study
title_sort optimal integration of intraneural somatosensory feedback with visual information: a single-case study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536542/
https://www.ncbi.nlm.nih.gov/pubmed/31133637
http://dx.doi.org/10.1038/s41598-019-43815-1
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