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Rab25 promotes erlotinib resistance by activating the β1 integrin/AKT/β‐catenin pathway in NSCLC
OBJECTIVES: Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI) has significant therapeutic efficacy in non‐small‐cell lung cancer (NSCLC) patients. However, acquired resistance is inevitable and limits the long‐term efficacy of EGFR‐TKI. Our study aimed to investigate the role of...
Autores principales: | Wang, Jianmin, Zhou, Pu, Wang, Xudong, Yu, Yongxin, Zhu, Guangkuo, Zheng, Linpeng, Xu, Zihan, Li, Feng, You, Qiai, Yang, Qiao, Zhuo, Wenlei, Sun, Jianguo, Chen, Zhengtang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536583/ https://www.ncbi.nlm.nih.gov/pubmed/30848009 http://dx.doi.org/10.1111/cpr.12592 |
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