Hypomethylation‐mediated activation of cancer/testis antigen KK‐LC‐1 facilitates hepatocellular carcinoma progression through activating the Notch1/Hes1 signalling

OBJECTIVES: Kita‐Kyushu lung cancer antigen‐1 (KK‐LC‐1) is a cancer/testis antigen reactivated in several human malignancies. So far, the major focus of studies on KK‐LC‐1 has been on its potential as diagnostic biomarker and immunotherapy target. However, its biological functions and molecular mech...

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Detalles Bibliográficos
Autores principales: Chen, Zhiqiang, Zuo, Xueliang, Pu, Liyong, Zhang, Yao, Han, Guoyong, Zhang, Long, Wu, Zhengshan, You, Wei, Qin, Jianjie, Dai, Xinzheng, Shen, Hongbing, Wang, Xuehao, Wu, Jindao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536599/
https://www.ncbi.nlm.nih.gov/pubmed/30895661
http://dx.doi.org/10.1111/cpr.12581

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