A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol

A new regioselective approach has been elaborated for the selective conversion of bio-based glycerol into the monomethyl derivative using sub/supercritical methanol. The reaction was realized in a batch process using three reactive components, namely, glycerol, methanol, and potassium carbonate to s...

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Detalles Bibliográficos
Autores principales: Bruniaux, Sophie, Varma, Rajender S., Len, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536655/
https://www.ncbi.nlm.nih.gov/pubmed/31165064
http://dx.doi.org/10.3389/fchem.2019.00357
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author Bruniaux, Sophie
Varma, Rajender S.
Len, Christophe
author_facet Bruniaux, Sophie
Varma, Rajender S.
Len, Christophe
author_sort Bruniaux, Sophie
collection PubMed
description A new regioselective approach has been elaborated for the selective conversion of bio-based glycerol into the monomethyl derivative using sub/supercritical methanol. The reaction was realized in a batch process using three reactive components, namely, glycerol, methanol, and potassium carbonate to selectively produce the 3-methoxypropan-1,2-diol in mild yields; the mechanism of the O-methylation has been delineated using labeled methanol and GC-MS experiments.
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spelling pubmed-65366552019-06-04 A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol Bruniaux, Sophie Varma, Rajender S. Len, Christophe Front Chem Chemistry A new regioselective approach has been elaborated for the selective conversion of bio-based glycerol into the monomethyl derivative using sub/supercritical methanol. The reaction was realized in a batch process using three reactive components, namely, glycerol, methanol, and potassium carbonate to selectively produce the 3-methoxypropan-1,2-diol in mild yields; the mechanism of the O-methylation has been delineated using labeled methanol and GC-MS experiments. Frontiers Media S.A. 2019-05-21 /pmc/articles/PMC6536655/ /pubmed/31165064 http://dx.doi.org/10.3389/fchem.2019.00357 Text en Copyright © 2019 Bruniaux, Varma and Len. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Bruniaux, Sophie
Varma, Rajender S.
Len, Christophe
A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol
title A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol
title_full A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol
title_fullStr A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol
title_full_unstemmed A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol
title_short A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol
title_sort novel strategy for selective o-methylation of glycerol in subcritical methanol
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536655/
https://www.ncbi.nlm.nih.gov/pubmed/31165064
http://dx.doi.org/10.3389/fchem.2019.00357
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