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Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation()

Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive pathway activation induces gastric tumors via mTORC1 activation in mouse genetic models. The purpose of this study was to determine whether human gastric adenocarcinomas are similarly dependent on Notch and...

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Detalles Bibliográficos
Autores principales:	Hibdon, Elise S., Razumilava, Nataliya, Keeley, Theresa M., Wong, Gabriela, Solanki, Sumeet, Shah, Yatrik M., Samuelson, Linda C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536707/ https://www.ncbi.nlm.nih.gov/pubmed/31129492 http://dx.doi.org/10.1016/j.neo.2019.05.002

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