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Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

Being an assembly of protein machines, cells depend on adequate supply of energetic molecules for retaining their homeodynamics. Consequently, mitochondria functionality is ensured by quality control systems and mitochondrial dynamics (fusion/fission). Similarly, proteome stability is maintained by...

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Detalles Bibliográficos
Autores principales: Gumeni, Sentiljana, Evangelakou, Zoi, Tsakiri, Eleni N., Scorrano, Luca, Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536731/
https://www.ncbi.nlm.nih.gov/pubmed/31132524
http://dx.doi.org/10.1016/j.redox.2019.101219

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