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Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection

Background: Intrapleural administration of compounds is a lung targeted, innovative therapeutic strategy for mesothelioma, which can be refined as a route for drug delivery that minimizes the potential for systemic toxicity. However, little is currently known about the retention of liposomal drugs a...

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Detalles Bibliográficos
Autores principales: Marazioti, A, Papadia, K, Giannou, A, Stathopoulos, GT, Antimisiaris, SG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536814/
https://www.ncbi.nlm.nih.gov/pubmed/31213801
http://dx.doi.org/10.2147/IJN.S202568