Germline mutation landscape of Chinese patients with familial breast/ovarian cancer in a panel of 22 susceptibility genes

Genetic testing for germline mutations in BRCA1/2 of patients with breast cancer (BC) is part of routine patient care. However, BRCA1/2 mutations account only for a fraction of familial BC. A custom panel of 22 gene sequencing was performed on each patient. Among the 481 female patients, 135 patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jiayu, Li, Weiwei, Shi, Yujian, Huang, Yan, Sun, Tao, Tang, Lili, Lu, Qing, Lei, Qiumo, Liao, Ning, Jin, Feng, Li, Hui, Huang, Tao, Qian, Jun, Pang, Danmei, Wang, Shusen, Fan, Peizhi, Wu, Xinhong, Lin, Ying, Qin, Haiyan, Xu, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536923/
https://www.ncbi.nlm.nih.gov/pubmed/30982232
http://dx.doi.org/10.1002/cam4.2093

Ejemplares similares

Ejemplares similares