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SIRT3 elicited an anti‐Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis

Cholangiocarcinoma (CCA) is an extremely invasive malignancy with late diagnosis and unfavorable prognosis. Surgery and chemotherapy are still not effective in improving outcomes in CCA patients. It is crucial to explore a novel therapeutic target for treating CCA. An NAD‐dependent deacetylase also...

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Detalles Bibliográficos
Autores principales:	Xu, Lei, Li, Yang, Zhou, Lixing, Dorfman, Robert Gregory, Liu, Li, Cai, Rui, Jiang, Chenfei, Tang, Dehua, Wang, Yuming, Zou, Xiaoping, Wang, Lei, Zhang, Mingming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536927/ https://www.ncbi.nlm.nih.gov/pubmed/30993888 http://dx.doi.org/10.1002/cam4.2089

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