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Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015

OBJECTIVE: To analyze the detection rates of colorectal cancer (CRC) and polyps by population‐based screening in Guangzhou. METHODS: From January 2011 to December 2015, the residents aged 30‐79 were selected for CRC screening. The residents were conducted Questionnaires and/or FOBT to assess high‐ri...

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Autores principales: Zhiqiang, Feng, Jie, Cao, Yuqiang, Nie, Chenghua, Gong, Hong, Wang, Zheng, Sun, Wanglin, Li, Yongjian, Zhou, Liping, Dai, Lizhong, Zeng, DeJian, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536937/
https://www.ncbi.nlm.nih.gov/pubmed/30927329
http://dx.doi.org/10.1002/cam4.1867
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author Zhiqiang, Feng
Jie, Cao
Yuqiang, Nie
Chenghua, Gong
Hong, Wang
Zheng, Sun
Wanglin, Li
Yongjian, Zhou
Liping, Dai
Lizhong, Zeng
DeJian, Zhao
author_facet Zhiqiang, Feng
Jie, Cao
Yuqiang, Nie
Chenghua, Gong
Hong, Wang
Zheng, Sun
Wanglin, Li
Yongjian, Zhou
Liping, Dai
Lizhong, Zeng
DeJian, Zhao
author_sort Zhiqiang, Feng
collection PubMed
description OBJECTIVE: To analyze the detection rates of colorectal cancer (CRC) and polyps by population‐based screening in Guangzhou. METHODS: From January 2011 to December 2015, the residents aged 30‐79 were selected for CRC screening. The residents were conducted Questionnaires and/or FOBT to assess high‐risk groups, the free colonoscopy examination was recommended, and the results were evaluated in detail. RESULTS: There were 98 927 residents involving screening, 5306 high‐risk residents identified (males 1859 and females 3447), and 4713 subjects underwent colonoscopy (males 1690 and females 3023). CRC was seen in 55 individuals (males 28 and females 27), and the detection rates in male were higher than in female (P = 0.019). And the detection rates increasing with age, for people over 60 years old, were obviously higher than those younger (x (2) = 18.64, P = 0.000924). The polyps were seen in 1458 (30.94%) cases, and 1420 subjects received pathological examination (adenomas 971 and non‐adenomatous polyps 449). Advanced adenomas were seen in 462 cases (males 240 and females 222) and 509 cases of non‐advanced adenomas (males 255 and females 254). For advanced adenomas, the detection rates in male were higher than female (14.20% vs 7.34%, P = 2.64 × 10(−14)). For the detection rates of adenomas or advanced adenomas by age, the people over 40 years were higher than younger (20.91% vs 3.61% P = 7.87 × 10(−6); 9.94% vs 2.41%, P = 0.009). CONCLUSIONS: For Guangzhou residents, the detection rates of CRC and adenoma were 1.17% and 20.60%. The detection rates of CRC increasing with age, for people over 60 years old, were obviously higher than those younger. But for people over 40 years, the detection rate of adenoma and advanced adenoma was higher than younger. So for people over 40 years, the CRC screening is recommended.
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spelling pubmed-65369372019-06-03 Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015 Zhiqiang, Feng Jie, Cao Yuqiang, Nie Chenghua, Gong Hong, Wang Zheng, Sun Wanglin, Li Yongjian, Zhou Liping, Dai Lizhong, Zeng DeJian, Zhao Cancer Med Cancer Prevention OBJECTIVE: To analyze the detection rates of colorectal cancer (CRC) and polyps by population‐based screening in Guangzhou. METHODS: From January 2011 to December 2015, the residents aged 30‐79 were selected for CRC screening. The residents were conducted Questionnaires and/or FOBT to assess high‐risk groups, the free colonoscopy examination was recommended, and the results were evaluated in detail. RESULTS: There were 98 927 residents involving screening, 5306 high‐risk residents identified (males 1859 and females 3447), and 4713 subjects underwent colonoscopy (males 1690 and females 3023). CRC was seen in 55 individuals (males 28 and females 27), and the detection rates in male were higher than in female (P = 0.019). And the detection rates increasing with age, for people over 60 years old, were obviously higher than those younger (x (2) = 18.64, P = 0.000924). The polyps were seen in 1458 (30.94%) cases, and 1420 subjects received pathological examination (adenomas 971 and non‐adenomatous polyps 449). Advanced adenomas were seen in 462 cases (males 240 and females 222) and 509 cases of non‐advanced adenomas (males 255 and females 254). For advanced adenomas, the detection rates in male were higher than female (14.20% vs 7.34%, P = 2.64 × 10(−14)). For the detection rates of adenomas or advanced adenomas by age, the people over 40 years were higher than younger (20.91% vs 3.61% P = 7.87 × 10(−6); 9.94% vs 2.41%, P = 0.009). CONCLUSIONS: For Guangzhou residents, the detection rates of CRC and adenoma were 1.17% and 20.60%. The detection rates of CRC increasing with age, for people over 60 years old, were obviously higher than those younger. But for people over 40 years, the detection rate of adenoma and advanced adenoma was higher than younger. So for people over 40 years, the CRC screening is recommended. John Wiley and Sons Inc. 2019-03-29 /pmc/articles/PMC6536937/ /pubmed/30927329 http://dx.doi.org/10.1002/cam4.1867 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Prevention
Zhiqiang, Feng
Jie, Cao
Yuqiang, Nie
Chenghua, Gong
Hong, Wang
Zheng, Sun
Wanglin, Li
Yongjian, Zhou
Liping, Dai
Lizhong, Zeng
DeJian, Zhao
Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
title Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
title_full Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
title_fullStr Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
title_full_unstemmed Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
title_short Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
title_sort analysis of population‐based colorectal cancer screening in guangzhou, 2011‐2015
topic Cancer Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536937/
https://www.ncbi.nlm.nih.gov/pubmed/30927329
http://dx.doi.org/10.1002/cam4.1867
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