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Zinc cooperates with p53 to inhibit the activity of mitochondrial aconitase through reactive oxygen species accumulation

Metabolic reprogramming is a central hallmark of cancer. Therefore, targeting metabolism may provide an effective strategy for identifying promising drug targets for cancer treatment. In prostate cancer, cells undergo metabolic transformation from zinc‐accumulating, citrate‐producing cells to citrat...

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Detalles Bibliográficos
Autores principales:	Xue, Ya‐Nan, Liu, Ya‐Nan, Su, Jing, Li, Jiu‐Ling, Wu, Yao, Guo, Rui, Yu, Bing‐Bing, Yan, Xiao‐Yu, Zhang, Li‐Chao, Sun, Lian‐Kun, Li, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536939/ https://www.ncbi.nlm.nih.gov/pubmed/30972978 http://dx.doi.org/10.1002/cam4.2130

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