Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women

An association between genetic variants in the vitamin D receptor (VDR) gene and epithelial ovarian cancer (EOC) was previously reported in women of African ancestry (AA). We sought to examine associations between genetic variants in VDR and additional genes from vitamin D biosynthesis and pathway t...

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Autores principales: Grant, Delores J., Manichaikul, Ani, Alberg, Anthony J., Bandera, Elisa V., Barnholtz‐Sloan, Jill, Bondy, Melissa, Cote, Michele L., Funkhouser, Ellen, Moorman, Patricia G., Peres, Lauren C., Peters, Edward S., Schwartz, Ann G., Terry, Paul D., Wang, Xin‐Qun, Keku, Temitope O., Hoyo, Cathrine, Berchuck, Andrew, Sandler, Dale P., Taylor, Jack A., O’Brien, Katie M., Velez Edwards, Digna R., Edwards, Todd L., Beeghly‐Fadiel, Alicia, Wentzensen, Nicolas, Pearce, Celeste Leigh, Wu, Anna H., Whittemore, Alice S., McGuire, Valerie, Sieh, Weiva, Rothstein, Joseph H., Modugno, Francesmary, Ness, Roberta, Moysich, Kirsten, Rossing, Mary Anne, Doherty, Jennifer A., Sellers, Thomas A., Permuth‐Way, Jennifer B., Monteiro, Alvaro N., Levine, Douglas A., Setiawan, Veronica Wendy, Haiman, Christopher A., LeMarchand, Loic, Wilkens, Lynne R., Karlan, Beth Y., Menon, Usha, Ramus, Susan, Gayther, Simon, Gentry‐Maharaj, Aleksandra, Terry, Kathryn L., Cramer, Daniel W., Goode, Ellen L., Larson, Melissa C., Kaufmann, Scott H., Cannioto, Rikki, Odunsi, Kunle, Etter, John L., Huang, Ruea‐Yea, Bernardini, Marcus Q., Tone, Alicia A., May, Taymaa, Goodman, Marc T., Thompson, Pamela J., Carney, Michael E., Tworoger, Shelley S., Poole, Elizabeth M., Lambrechts, Diether, Vergote, Ignace, Vanderstichele, Adriaan, Van Nieuwenhuysen, Els, Anton‐Culver, Hoda, Ziogas, Argyrios, Brenton, James D., Bjorge, Line, Salvensen, Helga B., Kiemeney, Lambertus A., Massuger, Leon F. A. G., Pejovic, Tanja, Bruegl, Amanda, Moffitt, Melissa, Cook, Linda, Le, Nhu D., Brooks‐Wilson, Angela, Kelemen, Linda E., Pharoah, Paul D.P., Song, Honglin, Campbell, Ian, Eccles, Diana, DeFazio, Anna, Kennedy, Catherine J., Schildkraut, Joellen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536963/
https://www.ncbi.nlm.nih.gov/pubmed/31001917
http://dx.doi.org/10.1002/cam4.1996

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