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Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients

BACKGROUND AND OBJECTIVES: Immediate postmastectomy breast reconstruction (IPBR) has gained wide popularity in China. We sought to clarify the prevalence and predictors of implant‐based vs autologous IPBR among Chinese patients. METHODS: A retrospective cohort study was performed using a prospective...

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Autores principales: Yin, Zhuming, Wang, Yan, Sun, Jingyan, Huang, Qingfeng, Liu, Jing, He, Shanshan, Han, Chunyong, Wang, Shu, Ding, Bowen, Yin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536967/
https://www.ncbi.nlm.nih.gov/pubmed/30950238
http://dx.doi.org/10.1002/cam4.2133
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author Yin, Zhuming
Wang, Yan
Sun, Jingyan
Huang, Qingfeng
Liu, Jing
He, Shanshan
Han, Chunyong
Wang, Shu
Ding, Bowen
Yin, Jian
author_facet Yin, Zhuming
Wang, Yan
Sun, Jingyan
Huang, Qingfeng
Liu, Jing
He, Shanshan
Han, Chunyong
Wang, Shu
Ding, Bowen
Yin, Jian
author_sort Yin, Zhuming
collection PubMed
description BACKGROUND AND OBJECTIVES: Immediate postmastectomy breast reconstruction (IPBR) has gained wide popularity in China. We sought to clarify the prevalence and predictors of implant‐based vs autologous IPBR among Chinese patients. METHODS: A retrospective cohort study was performed using a prospectively maintained database. Women who underwent IPBR during 2001‐2017 were included. The modality‐specific trends were deciphered by curve fitting analysis. The association of sociodemographic and oncological features with the decision for implant‐based vs autologous IPBR was investigated using multivariate logistic regression and structural equation modeling. RESULTS: Among 905 patients included in the study, 479 underwent implant‐based IPBR and 426 underwent autologous procedures. The implant/autologous ratio has increased exponentially over time. Multivariate analysis demonstrated that unmarried patients with BMI ≤ 24 kg/m(2), earlier clinical tumor stage, and preoperative pathological diagnosis of noninvasive lesion are more likely to choose implant‐based IPBR compared to autologous procedures. The indirect effects of age, mastectomy type, and neoadjuvant chemotherapy were further demonstrated by the structural equations. CONCLUSIONS: The sociodemographic and oncological features are directly or indirectly associated with the decision on type of IPBR. The findings may facilitate both patients and physicians to make a high‐quality decision by holistic evaluation of the sociodemographic and oncological features.
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spelling pubmed-65369672019-06-03 Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients Yin, Zhuming Wang, Yan Sun, Jingyan Huang, Qingfeng Liu, Jing He, Shanshan Han, Chunyong Wang, Shu Ding, Bowen Yin, Jian Cancer Med Clinical Cancer Research BACKGROUND AND OBJECTIVES: Immediate postmastectomy breast reconstruction (IPBR) has gained wide popularity in China. We sought to clarify the prevalence and predictors of implant‐based vs autologous IPBR among Chinese patients. METHODS: A retrospective cohort study was performed using a prospectively maintained database. Women who underwent IPBR during 2001‐2017 were included. The modality‐specific trends were deciphered by curve fitting analysis. The association of sociodemographic and oncological features with the decision for implant‐based vs autologous IPBR was investigated using multivariate logistic regression and structural equation modeling. RESULTS: Among 905 patients included in the study, 479 underwent implant‐based IPBR and 426 underwent autologous procedures. The implant/autologous ratio has increased exponentially over time. Multivariate analysis demonstrated that unmarried patients with BMI ≤ 24 kg/m(2), earlier clinical tumor stage, and preoperative pathological diagnosis of noninvasive lesion are more likely to choose implant‐based IPBR compared to autologous procedures. The indirect effects of age, mastectomy type, and neoadjuvant chemotherapy were further demonstrated by the structural equations. CONCLUSIONS: The sociodemographic and oncological features are directly or indirectly associated with the decision on type of IPBR. The findings may facilitate both patients and physicians to make a high‐quality decision by holistic evaluation of the sociodemographic and oncological features. John Wiley and Sons Inc. 2019-04-05 /pmc/articles/PMC6536967/ /pubmed/30950238 http://dx.doi.org/10.1002/cam4.2133 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Cancer Research
Yin, Zhuming
Wang, Yan
Sun, Jingyan
Huang, Qingfeng
Liu, Jing
He, Shanshan
Han, Chunyong
Wang, Shu
Ding, Bowen
Yin, Jian
Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients
title Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients
title_full Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients
title_fullStr Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients
title_full_unstemmed Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients
title_short Association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in Chinese patients
title_sort association of sociodemographic and oncological features with decision on implant‐based versus autologous immediate postmastectomy breast reconstruction in chinese patients
topic Clinical Cancer Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536967/
https://www.ncbi.nlm.nih.gov/pubmed/30950238
http://dx.doi.org/10.1002/cam4.2133
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