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Polymorphism rs2395655 affects LEDGF/p75 binding activity and p21WAF1/CIP1 gene expression in esophageal squamous cell carcinoma

p21WAF1/CIP1 (p21) plays critical roles in cell‐cycle regulation and DNA repair and is transcriptionally regulated through p53‐dependent or ‐independent pathways. Bioinformatic analysis predicated one stress‐response element (STRE) implicated in single nucleotide polymorphism (SNP) rs2395655 of the...

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Detalles Bibliográficos
Autores principales:	Guo, Rong, Ma, Yunan, Zhao, Min, Zhang, Wenlong, An, Guo, Chen, Baojun, Song, Yiping, Xu, Hui, Li, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536968/ https://www.ncbi.nlm.nih.gov/pubmed/30854807 http://dx.doi.org/10.1002/cam4.2067

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