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Cutaneous squamous cell carcinoma arising in hidradenitis suppurativa: A case report
We present a case of a 64-year-old man who presented with a rapidly growing tumor in the left buttock and intergluteal cleft area, which was affected by hidradenitis suppurativa. The patient was on tumor necrosis factor-alpha inhibitors for hidradenitis suppurativa for 2 years prior to the developme...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537059/ https://www.ncbi.nlm.nih.gov/pubmed/31205707 http://dx.doi.org/10.1177/2050313X19847359 |
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author | Roy, Catherine F Roy, Simon F Ghazawi, Feras M Patocskai, Erica Bélisle, Annie Dépeault, Alexandra |
author_facet | Roy, Catherine F Roy, Simon F Ghazawi, Feras M Patocskai, Erica Bélisle, Annie Dépeault, Alexandra |
author_sort | Roy, Catherine F |
collection | PubMed |
description | We present a case of a 64-year-old man who presented with a rapidly growing tumor in the left buttock and intergluteal cleft area, which was affected by hidradenitis suppurativa. The patient was on tumor necrosis factor-alpha inhibitors for hidradenitis suppurativa for 2 years prior to the development of the mass. Initial biopsy of the mass showed a well-differentiated squamous cell carcinoma with spindle cells and positive epithelial immunomarkers. Subsequent excisional biopsy of the tumor showed an infiltrating poorly differentiated squamous cell carcinoma composed of islands of atypical sarcomatoid spindle cells. Squamous cell carcinoma arising in hidradenitis suppurativa is a rare complication which may occur secondary to chronic inflammation and epidermal hyperproliferation in hidradenitis suppurativa–affected areas. |
format | Online Article Text |
id | pubmed-6537059 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-65370592019-06-14 Cutaneous squamous cell carcinoma arising in hidradenitis suppurativa: A case report Roy, Catherine F Roy, Simon F Ghazawi, Feras M Patocskai, Erica Bélisle, Annie Dépeault, Alexandra SAGE Open Med Case Rep JCMS Case Report We present a case of a 64-year-old man who presented with a rapidly growing tumor in the left buttock and intergluteal cleft area, which was affected by hidradenitis suppurativa. The patient was on tumor necrosis factor-alpha inhibitors for hidradenitis suppurativa for 2 years prior to the development of the mass. Initial biopsy of the mass showed a well-differentiated squamous cell carcinoma with spindle cells and positive epithelial immunomarkers. Subsequent excisional biopsy of the tumor showed an infiltrating poorly differentiated squamous cell carcinoma composed of islands of atypical sarcomatoid spindle cells. Squamous cell carcinoma arising in hidradenitis suppurativa is a rare complication which may occur secondary to chronic inflammation and epidermal hyperproliferation in hidradenitis suppurativa–affected areas. SAGE Publications 2019-05-17 /pmc/articles/PMC6537059/ /pubmed/31205707 http://dx.doi.org/10.1177/2050313X19847359 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | JCMS Case Report Roy, Catherine F Roy, Simon F Ghazawi, Feras M Patocskai, Erica Bélisle, Annie Dépeault, Alexandra Cutaneous squamous cell carcinoma arising in hidradenitis suppurativa: A case report |
title | Cutaneous squamous cell carcinoma arising in hidradenitis
suppurativa: A case report |
title_full | Cutaneous squamous cell carcinoma arising in hidradenitis
suppurativa: A case report |
title_fullStr | Cutaneous squamous cell carcinoma arising in hidradenitis
suppurativa: A case report |
title_full_unstemmed | Cutaneous squamous cell carcinoma arising in hidradenitis
suppurativa: A case report |
title_short | Cutaneous squamous cell carcinoma arising in hidradenitis
suppurativa: A case report |
title_sort | cutaneous squamous cell carcinoma arising in hidradenitis
suppurativa: a case report |
topic | JCMS Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537059/ https://www.ncbi.nlm.nih.gov/pubmed/31205707 http://dx.doi.org/10.1177/2050313X19847359 |
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