Cargando…

Oral lipoic acid as a treatment for acute optic neuritis: a blinded, placebo controlled randomized trial

BACKGROUND: Lipoic acid, an antioxidant, has beneficial effects in experimental acute optic neuritis and autoimmune encephalomyelitis. Optical coherence tomography can detect retinal nerve fiber layer thinning, representing axonal degeneration, approximately 3–6 months after acute optic neuritis. OB...

Descripción completa

Detalles Bibliográficos
Autores principales:	Falardeau, Julie, Fryman, Allison, Wanchu, Rohan, Marracci, Gail H, Mass, Michele, Wooliscroft, Lindsey, Bourdette, Dennis N, Murchison, Charles F, Hills, William L, Yadav, Vijayshree
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537072/ https://www.ncbi.nlm.nih.gov/pubmed/31205740 http://dx.doi.org/10.1177/2055217319850193

Ejemplares similares

Lipoic acid in secondary progressive MS: A randomized controlled pilot trial
por: Spain, Rebecca, et al.
Publicado: (2017)

Lipoic Acid Attenuates Inflammation via cAMP and Protein Kinase A Signaling
por: Salinthone, Sonemany, et al.
Publicado: (2010)

Lipoic Acid Pharmacokinetics at Baseline and 1 year in Secondary Progressive MS
por: Bittner, Frank, et al.
Publicado: (2017)

Omega-3 Fatty Acids for Depression in Multiple Sclerosis: A Randomized Pilot Study
por: Shinto, Lynne, et al.
Publicado: (2016)

The Effects of Omega-3 Fatty Acids on Matrix Metalloproteinase-9 Production and Cell Migration in Human Immune Cells: Implications for Multiple Sclerosis
por: Shinto, Lynne, et al.
Publicado: (2011)

Protocol for an exploratory, randomised, single-blind clinical trial of aerobic exercise to promote remyelination in multiple sclerosis
por: Wooliscroft, Lindsey, et al.
Publicado: (2023)

Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study
por: Yadav, Vijayshree, et al.
Publicado: (2012)

Enlarged perivascular spaces are not associated with vascular co-morbidities, clinical outcomes, and brain volumes in people with secondary progressive multiple sclerosis
por: Wooliscroft, Lindsey, et al.
Publicado: (2020)

A Randomized Placebo-Controlled Pilot Trial of Omega-3 Fatty Acids and Alpha Lipoic Acid in Alzheimer’s Disease
por: Shinto, Lynne, et al.
Publicado: (2014)

P02.183. Comparing the bioavailability of two forms of lipoic acid in multiple sclerosis
por: Salinthone, S, et al.
Publicado: (2012)

Falls in People with Multiple Sclerosis Compared with Falls in Healthy Controls
por: Mazumder, Rajarshi, et al.
Publicado: (2014)

Amiloride Clinical Trial In Optic Neuritis (ACTION) protocol: a randomised, double blind, placebo controlled trial
por: McKee, Justin B, et al.
Publicado: (2015)

Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial—study protocol
por: Diem, Ricarda, et al.
Publicado: (2016)

Effect of Alpha-Lipoic Acid Supplementation on Low-Grade Squamous Intraepithelial Lesions—Double-Blind, Randomized, Placebo-Controlled Trial
por: Divković, Anja, et al.
Publicado: (2022)

Innovations in the Management of Musculoskeletal Pain With Alpha-Lipoic Acid (IMPALA Trial): Study protocol for a Double-Blind, Randomized, Placebo-Controlled Crossover Trial of Alpha-Lipoic Acid for the Treatment of Fibromyalgia Pain
por: Gilron, Ian, et al.
Publicado: (2017)

The Effect of α-lipoic Acid on C-Reactive Protein Level: A Meta-analysis of Randomized, Double-Blind, and Placebo-Controlled Studies
por: Đukić, Ljiljana, et al.
Publicado: (2022)

Adjuvant Lipoic acid Injection in Sepsis treatment in China (ALIS study): protocol for a randomised, single-blind, placebo-controlled trial
por: Hu, Linhui, et al.
Publicado: (2023)

Does Alpha-lipoic Acid Supplement Regulate Blood Pressure? A Systematic Review of Randomized, Double-blind Placebo-controlled Clinical Trials
por: Mohammadi, Vida, et al.
Publicado: (2017)

Effect of add-on alpha lipoic acid on psychopathology in patients with treatment-resistant schizophrenia: a pilot randomized double-blind placebo-controlled trial
por: Mishra, Archana, et al.
Publicado: (2022)

Effects of alpha lipoic acid supplementation on serum lipid profile in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical trial
por: Ahmadi, Mahbubeh, et al.
Publicado: (2022)

Early alpha-lipoic acid therapy protects from degeneration of the inner retinal layers and vision loss in an experimental autoimmune encephalomyelitis-optic neuritis model
por: Dietrich, Michael, et al.
Publicado: (2018)

Effect of vitamin A on recovery from the acute phase of multiple sclerosis-related optic neuritis, double-blind, randomized, placebo-controlled trial
por: Rahimi-Dehgolan, Shiva, et al.
Publicado: (2023)

Effect of Alpha-Lipoic Acid Supplementation on Endothelial Function and Cardiovascular Risk Factors in Overweight/Obese Youths: A Double-Blind, Placebo-Controlled Randomized Trial
por: Tromba, Luciana, et al.
Publicado: (2019)

Multiple Sclerosis
por: Lane, Michael, et al.
Publicado: (2020)

The effect of alpha-lipoic acid supplementation on anthropometric indices and food intake in patients who experienced stroke: A randomized, double-blind, placebo-controlled clinical trial
por: Mohammadi, Vida, et al.
Publicado: (2017)

Autoantibodies and Sjogren’s Syndrome in Multiple Sclerosis, a Reappraisal
por: Solomon, Andrew J., et al.
Publicado: (2013)

Participant Perspectives on Community Qigong for People with Multiple Sclerosis
por: Buttolph, Lita, et al.
Publicado: (2023)

A microwave method for plastic embedding of nervous tissue for light and electron microscopy
por: Calkins, Evan, et al.
Publicado: (2019)

Optic Neuritis
por: Dooley, Mary Caitlin, et al.
Publicado: (2010)

Optic Neuritis
Publicado: (1890)

Brachial Neuritis
Publicado: (1904)

Arsenical Neuritis
Publicado: (1904)

Peripheral Neuritis
por: Napier, L. E.
Publicado: (1943)

Peripheral Neuritis
por: Deb, J. P.
Publicado: (1943)

On Peripheral Neuritis
Publicado: (1893)

Neuritis and Neuralgia
Publicado: (1895)

Serum Neuritis
por: Napier, William
Publicado: (1945)

Tubercular Neuritis
por: James, Alexander
Publicado: (1899)

Multiple Neuritis
por: Holmes, T. M.
Publicado: (1887)

Multiple Neuritis
por: Hardman, W. B.
Publicado: (1888)

Cannot write session to /tmp/vufind_sessions/sess_lci68p5mdbnttjmska99opaive