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Somatic mutation and clonal expansions in human tissues
Recent sequencing studies on healthy skin and esophagus have found that, as we age, these tissues become colonized by mutant clones of cells carrying driver mutations in traditional cancer genes. This comment summarizes these findings and discusses their possible implications for our understanding o...
Autor principal: | Martincorena, Inigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537184/ https://www.ncbi.nlm.nih.gov/pubmed/31138277 http://dx.doi.org/10.1186/s13073-019-0648-4 |
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