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Somatic mutation and clonal expansions in human tissues

Recent sequencing studies on healthy skin and esophagus have found that, as we age, these tissues become colonized by mutant clones of cells carrying driver mutations in traditional cancer genes. This comment summarizes these findings and discusses their possible implications for our understanding o...

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Detalles Bibliográficos
Autor principal: Martincorena, Inigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537184/
https://www.ncbi.nlm.nih.gov/pubmed/31138277
http://dx.doi.org/10.1186/s13073-019-0648-4

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